SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks

Matthew J. Rardin, Wenjuan He, Yuya Nishida, +21

Cell Metabolism

Mitochondrial FunctionMitochondrial DynamicAutophagyMolecular BiologyMitochondrial Lysine Succinylome +3

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target

Yuya Nishida, Matthew J. Rardin, Chris Carrico, +8

Molecular Cell

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice

John C. Newman, Anthony J. Covarrubias, Minghao Zhao, +6

Cell Metabolism

Alzheimer's DiseaseAgingImproves MemoryLongevityDementia +8

A molecular mechanism for Wnt ligand-specific signaling

Marie Eubelen, Naguissa Bostaille, Pauline Cabochette, +9

Science

Developmental BiologySignal TransductionSignaling PathwayMolecular PathwayWnt Ligand-specific Signaling +7

Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism

Philipp Gut, Bernat Baeza-Raja, Olov Andersson, +7

Nature Chemical Biology

BiochemistryMetabolic RegulationWhole-organism ScreeningMetabolomicsMetabolism +1

Adenosine Signaling Promotes Regeneration of Pancreatic β Cells In Vivo

Olov Andersson, Bruce A. Adams, Daniel Yoo, +5

Cell Metabolism

Regenerative MedicineMolecular PhysiologySignal TransductionPancreatic CancerPhysiology +6

SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK

Linh Ho, Allen Sam Titus, Kushal K. Banerjee, +8

Aging

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

Alan A. Cohen, Brian K. Kennedy, Ulrich Anglas, +35

Mechanisms of Ageing and Development

BiologyLifespan ExtensionAnti-agingAgingGeriatrics +9

Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish

Agata Jurczyk, Nicole M. Roy, Rabia Bajwa, +12

General and Comparative Endocrinology

Animal PhysiologyBiologyDynamic GlucoregulationEnergy MetabolismDevelopmental Biology +9

Acute Toxicity and Quality of Life After Dose-Intensified Salvage Radiation Therapy for Biochemically Recurrent Prostate Cancer After Prostatectomy: First Results of the Randomized Trial SAKK 09/10

Pirus Ghadjar, Stefanie Hayoz, Jürg Bernhard, +20

Journal of Clinical Oncology