Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

Tobias Junt, E. Ashley Moseman, Matteo Iannacone, +10

Nature

Viral PersistenceViral PathogenesisImmunologyB CellsVirology +4

HMGB1 is an endogenous immune adjuvant released by necrotic cells

Patrizia Rovere‐Querini, Annalisa Capobianco, Paola Scaffidi, +9

EMBO Reports

InflammationAutoimmune DiseaseEndogenous Immune AdjuvantImmunologyCell Death +8

Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine

Roksana M. Pirzgalska, Elsa Seixas, Jason S. Seidman, +19

Nature Medicine

ObesityMetabolic SyndromeInflammationEnergy HomeostasisPhysiology +9

Platelets mediate cytotoxic T lymphocyte–induced liver damage

Matteo Iannacone, Giovanni Sitia, Masanori Isogawa, +6

Nature Medicine

Liver DamageHepatologyLiver PhysiologyImmunologyHematology +6

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus

Matteo Iannacone, E. Ashley Moseman, Elena Tonti, +6

Nature

Peripheral InfectionNeurovirologyNeuroinfectious DiseasesMedicineImmunology +8

CD8+ T Cells Orchestrate pDC-XCR1+ Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming

Anna Brewitz, Sarah Eickhoff, Sabrina Dähling, +13

Immunity

Signal TransductionFunctional CooperativityAdaptive Immune SystemCell InteractionImmunology +7

Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria

Florian Gaertner, Zerkah Ahmad, Gerhild Rosenberger, +27

Cell

Pathogen TransmissionMicrobiologyBundle Bacteria

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B

Giovanni Sitia, Roberto Aiolfi, Pietro Di Lucia, +8

Proceedings of the National Academy of Sciences

Immunosurveillance of the Liver by Intravascular Effector CD8 + T Cells

Luca G. Guidotti, Donato Inverso, Laura Sironi, +17

Cell

Clinical ImmunologyHepatic DisordersHepatologyAutoimmune DiseaseLiver Physiology +9

IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer

Nicoletta Caronni, Federica La Terza, Francesco Maria Vittoria, +37

Nature

InflammationCytokinePancreatic CancerImmunologyChronic Inflammation +4