William A. Freed-Pastor

Author

Massachusetts Institute of Technology ORCID

Also Known As

Freed-Pastor, William A, Freed-Pastor, William Allen, Will Freed-Pastor, William A Freed-Pastor, William A. Freed-Pastor, William Freed-Pastor, William A. Freed-Pastor

Publications

4.7K

Citations

H-Index

Concepts

All Affiliations

Massachusetts Institute of Technology Harvard University Dana-Farber Cancer Institute Broad Institute Massachusetts General Hospital

About

William A. Freed-Pastor is an author at Massachusetts Institute of Technology specializing in medicine, cell biology, and tumor biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	13	13	2.8K
2	Cell Biology	9	9	2.4K
3	Natural Sciences	3	3	369
4	Engineering	2	2	90
5	Health Sciences	1	1	366

William A. Freed-Pastor

Publications

3.3K

Citations

H-Index

Page 1

	Year	Citations
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway William A. Freed-Pastor, Hideaki Mizuno, Xi Zhao, Cell MedicineMevalonate PathwayMammary GlandBreast CancerTumor Suppressor	2012	850
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression Sung‐Hwan Moon, Chun‐Hao Huang, Shauna L Houlihan, Cell MedicineMevalonate PathwayTumor SuppressorCancer BiologyCell Biology	2018	442
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo, Nature Genetics Trajectory AnalysisTumor BiologyPancreatic CancerTumor HeterogeneitySpatial Transcriptome Profiling	2022	366
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution Dian Yang, Matthew G. Jones, Santiago Naranjo, Cell Lineage PlasticityCell LineageDevelopmental BiologyTumor HeterogeneitySingle Cell Sequencing	2022	310
Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes Jason M. Schenkel, Rebecca H. Herbst, David Canner, Immunity	2021	251
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer William A. Freed-Pastor, Laurens J. Lambert, Zackery A. Ely, Cancer Cell Maintains Immune EvasionCancer ImmunosurveillancePancreatic CancerMedicineImmunology	2021	245
Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate <i>VEGFR2</i> in breast cancer cells Neil T. Pfister, Vitalay Fomin, Kausik Regunath, Genes & Development	2015	137
Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes Judith F. Kribelbauer, Oleg Laptenko, Siying Chen, Cell Reports ChromatinChromatin RemodelingNatural SciencesGeneticsDna Methylation	2017	133
Accurate and sensitive quantification of protein-DNA binding affinity Chaitanya Rastogi, H. Tomas Rube, Judith F. Kribelbauer, Proceedings of the National Academy of Sciences Transcriptional RegulationFunctional GenomicsNatural SciencesGeneticsGene Recognition	2018	119
The p53 C Terminus Controls Site-Specific DNA Binding and Promotes Structural Changes within the Central DNA Binding Domain Oleg Laptenko, Idit Shiff, William A. Freed-Pastor, Molecular Cell ChromatinCell RegulationPromotes Structural ChangesNatural SciencesMolecular Regulation	2015	117

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