Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas

Rama Rao Malla, Sreelatha Gopinath, Kiranmai Alapati, +5

PLoS ONE

Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression

Sreelatha Gopinath, Rama Rao Malla, Kiranmai Alapati, +4

Carcinogenesis

Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in glioma

Rama Rao Malla, S Gopinath, Christopher S. Gondi, +4

Cancer Gene Therapy

Tumor BiologyAngiogenesisGliomaCathepsin BMedicine +9

uPAR and cathepsin B inhibition enhanced radiation-induced apoptosis in gliomainitiating cells

Rama Rao Malla, S Gopinath, Kiranmai Alapati, +3

Neuro-Oncology

ApoptosisCathepsin B InhibitionCell DeathRadiation BiologyCancer Biology +19

uPAR and cathepsin B-mediated compartmentalization of JNK regulates the migration of glioma-initiating cells

Kiranmai Alapati, Divya Kesanakurti, Jasti S. Rao, +1

Stem Cell Research

<i>Retracted</i>: Knockdown of cathepsin B and u<scp>PAR</scp> inhibits <scp>CD</scp>151 and α3β1 integrin‐mediated cell adhesion and invasion in glioma

Rama Rao Malla, Sreelatha Gopinath, Kiranmai Alapati, +3

Molecular Carcinogenesis

uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells

Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, +2

International Journal of Oncology

High-grade GliomasPkc ζGliomaCancer BiologyTumor Biology +14

Co-Depletion of Cathepsin B and uPAR Induces G0/G1 Arrest in Glioma via FOXO3a Mediated p27Kip1 Upregulation

Sreelatha Gopinath, Rama Rao Malla, Christopher S. Gondi, +6

PLoS ONE

Cord Blood Stem Cells Inhibit Epidermal Growth Factor Receptor Translocation to Mitochondria in Glioblastoma

Venkata Ramesh Dasari, Kiran Kumar Velpula, Kiranmai Alapati, +2

PLoS ONE

RETRACTED ARTICLE: uPAR and cathepsin B downregulation induces apoptosis by targeting calcineurin A to BAD via Bcl-2 in glioma

Rama Rao Malla, Sreelatha Gopinath, Christopher S. Gondi, +4

Journal of Neuro-Oncology

GliomaMedicineApoptosisCell DeathCancer Biology +6