An intranasal vaccine durably protects against SARS-CoV-2 variants in mice

Ahmed O. Hassan, Swathi Shrihari, Matthew J. Gorman, +16

Cell Reports

A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope

Laura A. VanBlargan, Lucas J. Adams, Zhuoming Liu, +22

Immunity

VaccinationNeutralizing Sars-cov-2 AntibodyVaccine TargetImmunologyVirology +4

BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

Yu Xia, Katalin Sándor, Joy A. Pai, +13

Immunity

Autoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunologyAutoimmunity +7

Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines

Chieh-Yu Liang, Saravanan Raju, Zhuoming Liu, +17

Nature

VaccinationVaccine DevelopmentWuhan-1 Mrna VaccinesImmunologyVaccine Design +4

SpDamID: Marking DNA Bound by Protein Complexes Identifies Notch-Dimer Responsive Enhancers

Matthew R. Hass, Hien-haw Liow, Xiaoting Chen, +13

Molecular Cell

ChromatinNatural SciencesMarking Dna BoundGenomic MechanismDna Replication +6

Kinase domain dimerization drives RIPK3-dependent necroptosis

Saravanan Raju, Daniel M. Whalen, Meron Mengistu, +6

Science Signaling

A chikungunya virus–like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans

Saravanan Raju, Lucas J. Adams, James T. Earnest, +5

Science Translational Medicine

Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection

Baoling Ying, Tamarand L. Darling, Pritesh Desai, +12

Nature Immunology

Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8

Ofer Zimmerman, Maxwell I. Zimmerman, Saravanan Raju, +22

Cell

Virus StructurePathogenesisImmunologyVirologyAlphavirus Receptor Mxra8 +2

Hemophagocytic Lymphohistiocytosis Syndrome in Dengue Hemorrhagic Fever

Saravanan Raju, Shantaraman Kalyanaraman, Krishnan Swaminathan, +2

The Indian Journal of Pediatrics

PathogenesisHematologyImmunologyDengue Hemorrhagic FeverMedicine +1