Loss of Connexin36 Channels Alters β-Cell Coupling, Islet Synchronization of Glucose-Induced Ca2+ and Insulin Oscillations, and Basal Insulin Release

Magalie A. Ravier, Martin Güldenagel, Anne Charollais, +7

Diabetes

Expression of Connexin36 in the adult and developing rat brain

Natale Belluardo, Giuseppa Mudò, Angela Trovato Salinaro, +7

Brain Research

Developmental BiologyMolecular NeuroscienceSynaptic SignalingBrain DevelopmentNeuroscience +5

Targeting Pannexin1 Improves Seizure Outcome

Marcelo F. Santiago, Jana Velı́šková, Naman K. Patel, +5

PLoS ONE

Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics

Stephan Speier, Asllan Gjinovci, Anne Charollais, +2

Diabetes

Cx36-gap JunctionsNeurotransmissionCellular PhysiologyInsulin SignalingHyperpolarization (Biology) +15

Cx36 preferentially connects beta-cells within pancreatic islets.

Véronique Serre‐Beinier, Sabine Le Gurun, Natale Belluardo, +5

Diabetes

Molecular PhysiologySignal TransductionPancreatic IsletsCell InteractionImmunology +8

Junctional communication of pancreatic β cells contributes to the control of insulin secretion and glucose tolerance

Anne Charollais, Asllan Gjinovci, Joachim Huarte, +11

Journal of Clinical Investigation

Junctional CommunicationGlucose ToleranceInsulin SignalingCellular PhysiologyBeta Cells +14

Cx36 makes channels coupling human pancreatic β-cells, and correlates with insulin expression

Véronique Serre‐Beinier, Domenico Bosco, Laurence Zulianello, +13

Human Molecular Genetics

Cellular PhysiologyInsulin SignalingGastrointestinal Peptide HormoneCell InteractionIntercellular Communication +15

Adequate connexin-mediated coupling is required for proper insulin production.

Cristina Vozzi, Susanne Ullrich, Anne Charollais, +3

The Journal of Cell Biology

Systems BiologySignal TransductionMolecular PhysiologyBiochemistryProper Insulin Production +13

Islet‐cell‐to‐cell communication as basis for normal insulin secretion

Sabine Bavamian, Philippe Klee, Aurore Britan, +5

Diabetes Obesity and Metabolism

Subcellular Distribution and Function of Rab3A, B, C, and D Isoforms in Insulin-Secreting Cells

Mariella Iezzi, Gérard Escher, Paolo Meda, +5

Molecular Endocrinology