Glioblastoma Subclasses Can Be Defined by Activity among Signal Transduction Pathways and Associated Genomic Alterations

Cameron Brennan, Hiroyuki Momota, Dolores Hambardzumyan, +4

PLoS ONE

Gli Activity Correlates with Tumor Grade in Platelet-Derived Growth Factor–Induced Gliomas

Oren J. Becher, Dolores Hambardzumyan, Elena I. Fomchenko, +9

Cancer Research

Perifosine Inhibits Multiple Signaling Pathways in Glial Progenitors and Cooperates With Temozolomide to Arrest Cell Proliferation in Gliomas <i>In vivo</i>

Hiroyuki Momota, Edward Nerio, Eric C. Holland

Cancer Research

Chemoprevention StrategyApoptosisCell DeathGlial ProgenitorsCellular Pharmacology +17

The Global DNA Methylation Surrogate LINE-1 Methylation Is Correlated with MGMT Promoter Methylation and Is a Better Prognostic Factor for Glioma

Fumiharu Ohka, Atsushi Natsume, Kazuya Motomura, +13

PLoS ONE

Mgmt Promoter MethylationEpigenetic ChangeDna MethylationPathologyHigh-grade Gliomas +20

Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase

Yuki Ohkawa, Hiroyuki Momota, Akira Kato, +6

Journal of Biological Chemistry

Neuro-oncologyTumor InnervationGliomaImmunologyHigh-grade Gliomas +7

Constitutive Activation of Raf-1 Induces Glioma Formation in Mice

Yelena Lyustikman, Hiroyuki Momota, William Pao, +1

Neoplasia

Neuro-oncologyRas ActivityActivated KrasSignaling PathwayGlioma +11

Enhancement of malignant properties of human glioma cells by ganglioside GD3/GD2

Taiji Iwasawa, Pu Zhang, Yuki Ohkawa, +6

International Journal of Oncology

Tumor InnervationImmunologyImmunotherapeuticsHigh-grade GliomasCancer Biology +20

Immunohistochemical analysis‐based proteomic subclassification of newly diagnosed glioblastomas

Kazuya Motomura, Atsushi Natsume, Reiko Watanabe, +13

Cancer Science

Proteomic TechnologyNeuro-oncologyProteomic SubclassificationGliomaTumor Heterogeneity +12

Secondary hematological malignancies associated with temozolomide in patients with glioma

Hiroyuki Momota, Yusuke Narita, Yasuji Miyakita, +1

Neuro-Oncology

c-Myc and β-catenin cooperate with loss of p53 to generate multiple members of the primitive neuroectodermal tumor family in mice

Hiroyuki Momota, Alan H. Shih, Mark Edgar, +1

Oncogene

Multiple MembersTumor BiologyDevelopmental BiologyMedicineβ-Catenin Cooperate +4