Jeffrey J. Alberts

Pharmacokinetics, Metabolism, and Excretion of the Glycogen Synthase Kinase-3 Inhibitor LY2090314 in Rats, Dogs, and Humans: A Case Study in Rapid Clearance by Extensive Metabolism with Low Circulating Metabolite Exposure

Maciej J. Zamek‐Gliszczynski, Trent L. Abraham, Jeffrey J. Alberts et al. · Drug Metabolism and Disposition · 2013 · 39 citations · Full text

Identification of human UDP-glucuronosyltransferases catalyzing hepatic 1α,25-dihydroxyvitamin D3 conjugation

Takanori Hashizume, Yang Xu, Michael A. Mohutsky et al. · Biochemical Pharmacology · 2007 · 31 citations · Full text

Biochemistry, Liver Physiology, Biochemical Genetics +4

Physiologically‐Based Pharmacokinetic Modeling of Atorvastatin Incorporating Delayed Gastric Emptying and Acid‐to‐Lactone Conversion

Bridget L. Morse, Jeffrey J. Alberts, Maria M. Posada et al. · CPT Pharmacometrics & Systems Pharmacology · 2019 · 29 citations · Full text

Lactone Form, Pharmacokinetic Modeling, Biochemistry +14

Identification and Mitigation of Reactive Metabolites of 2-Aminoimidazole-Containing Microsomal Prostaglandin E Synthase-1 Inhibitors Terminated Due to Clinical Drug-Induced Liver Injury

Bryan H. Norman, Matthew J. Fisher, Matthew A. Schiffler et al. · Journal of Medicinal Chemistry · 2018 · 26 citations

Medicinal Chemistry, Reactive Metabolites, Biochemistry +15

Development of a rapid and sensitive multiple reaction monitoring proteomic approach for quantification of transporters in human liver tissue

Li Wang, Kasi J. Rubadue, Jeffrey J. Alberts et al. · Journal of Chromatography B · 2017 · 14 citations

Proteomic Technology, Systems Biology, Biochemistry +10