Patricia L. Karjian

Rationally Designed High-Affinity 2-Amino-6-halopurine Heat Shock Protein 90 Inhibitors That Exhibit Potent Antitumor Activity

Srinivas Rao Kasibhatla, Kevin Hong, Marco A. Biamonte et al. · Journal of Medicinal Chemistry · 2007 · 125 citations · Full text

Medicine, Oncology, Pharmacology +14

Orally Active Purine-Based Inhibitors of the Heat Shock Protein 90

Marco A. Biamonte, Jiandong Shi, Kevin Hong et al. · Journal of Medicinal Chemistry · 2005 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

A high-affinity conformation of Hsp90 confers tumor selectivity on Hsp90 inhibitors

Adeela Kamal, John Sensintaffar, Patricia L. Karjian et al. · Cancer Research · 2004 · 35 citations

Medicine, Oncology, Pharmacology +13

Nucleoside transport inhibitors, dipyridamole and p-nitrobenzylthioinosine, selectively potentiate the antitumor activity of NB1011

Christopher R. Boyer, Patricia L. Karjian, Geoffrey M. Wahl et al. · Anti-Cancer Drugs · 2002 · 24 citations

Medicine, Oncology, Pharmacology +12

Dimeric ansamycins—A new class of antitumor Hsp90 modulators with prolonged inhibitory activity

Hong Zhang, Yong‐Ching Yang, Lin Zhang et al. · International Journal of Cancer · 2006 · 18 citations

Medicine, Medicinal Chemistry, Pharmacology +14