Claudia Manriquez Roman

Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma

Reona Sakemura, Mehrdad Hefazi, Elizabeth L. Siegler et al. · Blood · 2022 · 130 citations · Full text

Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia

Michelle J. Cox, Fabrice Lucien, Reona Sakemura et al. · Molecular Therapy · 2020 · 72 citations · Full text

GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity

Michelle J. Cox, Claudia Manriquez Roman, Erin E. Tapper et al. · Leukemia · 2022 · 36 citations · Full text

Cancer Immunosurveillance, Gm-csf Disruption, T-regulatory Cell +9

Development of a Clinically Relevant Reporter for Chimeric Antigen Receptor T-cell Expansion, Trafficking, and Toxicity

Reona Sakemura, Aditya Bansal, Elizabeth L. Siegler et al. · Cancer Immunology Research · 2021 · 27 citations · Full text

IL-4 drives exhaustion of CD8+ CART cells

Carli M. Stewart, Elizabeth L. Siegler, Reona Sakemura et al. · Nature Communications · 2024 · 27 citations · Full text