Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells

Piotr Kaźmierczak, Hirofumi Sakaguchi, Joshua Tokita, +4

Nature

Skin DevelopmentProtein FunctionDevelopmental BiologySignal TransductionCell Signaling +12

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

Wei Xiong, Nicolas Grillet, Heather M. Elledge, +5

Cell

MechanobiologyMechanotransduction MachinerySignal TransductionCochlear NucleiPhysiology +10

The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions

Jan Siemens, Piotr Kaźmierczak, Anna Reynolds, +3

Proceedings of the National Academy of Sciences

Type 1Usher Syndrome ProteinsSignal TransductionCause DeafnessSignaling Pathway +13

Physical and Functional Interaction between Protocadherin 15 and Myosin VIIa in Mechanosensory Hair Cells

Mathias Senften, Martin Schwander, Piotr Kaźmierczak, +8

Journal of Neuroscience

Molecular RegulationGeneticsFunctional InteractionMolecular BiologyCytoskeleton +20

Harmonin Mutations Cause Mechanotransduction Defects in Cochlear Hair Cells

Nicolas Grillet, Wei Xiong, Anna Reynolds, +11

Neuron

Genome InstabilityGenetic DisorderGeneticsMolecular GeneticsMutagenesis +3

A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells

Martin Schwander, Wei Xiong, Joshua Tokita, +11

Proceedings of the National Academy of Sciences

GeneticsMolecular GeneticsDisease Gene IdentificationMendelian DisorderCell Development +19

Virus-associated down-regulation of the gene encoding cryparin, an abundant cell-surface protein from the chestnut blight fungus, Cryphonectria parasitica

L. Zhang, Deborah Kay Villalon, Yongxu Sun, +2

Gene

BiologyChestnut Blight FungusCryphonectria ParasiticaFungal Cell BiologyNatural Sciences +8

Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells

Iwona A. Ciechomska, Beata Pyrzyńska, Piotr Kaźmierczak, +1

Oncogene

Akt Kinase SignallingSignaling PathwayCell RegulationGliomaFasl Expression +10

Hypovirulence-associated traits induced by a mycovirus of Cryphonectria parasitica are mimicked by targeted inactivation of a host gene.

L Zhang, A. C. Churchill, Piotr Kaźmierczak, +2

Molecular and Cellular Biology

Fungal VirusGeneticsViral PathogenesisPlant PathologyMolecular Genetics +19

Membrane-Associated Replication of an Unencapsidated Double-Strand RNA of the Fungus, Cryphonectria parasitica

Tzion Fahima, Piotr Kaźmierczak, D. R. Hansen, +2

Virology

BiologyCryphonectria ParasiticaFungal Cell BiologyNatural SciencesMolecular Biology +5