Synthesis and Evaluation of Keto-Glutamine Analogues as Potent Inhibitors of Severe Acute Respiratory Syndrome 3CL^pro

Rajendra P. Jain, Hanna Pettersson, Jianmin Zhang, +8

Journal of Medicinal Chemistry

Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation

Marjan Shafaati, Amelia Marutle, Hanna Pettersson, +6

Journal of Lipid Research

Sporadic AlzheimerNeurochemical BiomarkersSwedish App 670/671Vicious CircleAlzheimer's Disease +15

Design, Synthesis, and Evaluation of Inhibitors for Severe Acute Respiratory Syndrome 3C-Like Protease Based on Phthalhydrazide Ketones or Heteroaromatic Esters

Jianmin Zhang, Hanna Pettersson, Carly Huitema, +5

Journal of Medicinal Chemistry

Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo

Marjan Shafaati, Maria Olin, Ann Båvner, +5

Journal of Internal Medicine

Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1)

Tara Fryatt, Hanna Pettersson, Walter T. Gardipee, +5

Bioorganic & Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryQuinone OxidoreductaseBiochemistryMedicine +6

A high ratio of insulin-like growth factor II/insulin-like growth factor binding protein 2 messenger RNA as a marker for anaplasia in meningiomas.

A C Nordqvist, Michel Peyrard, Hanna Pettersson, +4

PubMed

Developmental BiologyHigh RatioGrowth HormoneHuman GrowthInsulin-like Growth Factors +11

Off-Target Effects in Transgenic Mice: Characterization of Dopamine Transporter (DAT)-Cre Transgenic Mouse Lines Exposes Multiple Non-Dopaminergic Neuronal Clusters Available for Selective Targeting within Limbic Neurocircuitry

Maria Papathanou, Sylvie Dumas, Hanna Pettersson, +1

eNeuro

Validation of an isotope dilution gas chromatography–mass spectrometry method for analysis of 7-oxygenated campesterol and sitosterol in human serum

Constanze Husche, Oliver Weingärtner, Hanna Pettersson, +4

Chemistry and Physics of Lipids

BiochemistryGas ChromatographyMedicineBioanalysisMass Spectrometry +9

Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio

Maria Papathanou, Meaghan C. Creed, Matthijs C. Dorst, +7

Frontiers in Neural Circuits

An Episulfide Cation (Thiiranium Ring) Trapped in the Active Site of HAV 3C Proteinase Inactivated by Peptide-based Ketone Inhibitors

Yin Jiang, M.M. Cherney, Ernst M. Bergmann, +6

Journal of Molecular Biology

Protein ChemistryMedicinal ChemistryThiiranium RingBiochemistryEpisulfide Cation +9