Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

Jia Li-Hawkins, Mats Gåfvels, Maria Olin, +5

Journal of Clinical Investigation

Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

Jia Li-Hawkins, Mats Gåfvels, Maria Olin, +5

Journal of Clinical Investigation

CholangiopathiesCholangiocyte BiologyOxidative StressNegative Feedback RegulationMolecular Pharmacology +18

Brain Cholesterol Synthesis in Mice Is Affected by High Dose of Simvastatin but Not of Pravastatin

Karin Thelen, Katharina Rentsch, Ursula Gutteck, +5

Journal of Pharmacology and Experimental Therapeutics

Studies on the Transcriptional Regulation of Cholesterol 24-Hydroxylase (CYP46A1)

Yoshihiko Ohyama, Steve Meaney, Maura Heverin, +8

Journal of Biological Chemistry

Transcriptional RegulationMolecular NeuroscienceBrain CholesterolBiochemistryCholesterol Synthesis +10

Effects of a Disrupted Blood-Brain Barrier on Cholesterol Homeostasis in the Brain

Ahmed Saeed, Guillem Genové, Tian Li, +9

Journal of Biological Chemistry

Metabolic SyndromeLipid DisorderDisrupted Blood-brain BarrierBlood–brain BarrierPhysiology +12

Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation

Marjan Shafaati, Amelia Marutle, Hanna Pettersson, +6

Journal of Lipid Research

Sporadic AlzheimerNeurochemical BiomarkersSwedish App 670/671Vicious CircleAlzheimer's Disease +15

Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?

Silvia Maioli, Ann Båvner, Zeina Ali, +9

PLoS ONE

NeuropsychologyBrain FunctionNeurotransmitterCyp46a1 Transgenic MiceSynaptic Signaling +17

Structure and Chromosomal Assignment of the Sterol 12α-Hydroxylase Gene (CYP8B1) in Human and Mouse: Eukaryotic Cytochrome P-450 Gene Devoid of Introns

Mats Gåfvels, Maria Olin, Bhanu P. Chowdhary, +5

Genomics

Chromosomal AssignmentMolecular ResearchBiochemistryNatural SciencesGenetics +6

Molecular Cloning and Expression of Rabbit Sterol 12α-Hydroxylase

Gösta Eggertsen, Maria Olin, Hiroko Ishida, +4

Journal of Biological Chemistry

Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo

Marjan Shafaati, Maria Olin, Ann Båvner, +5

Journal of Internal Medicine