α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas

Eswari Dodagatta-Marri, Dominique S. Meyer, Melissa Quino Reeves, +21

Journal for ImmunoTherapy of Cancer

Long-Term Outcomes of Repeat Hepatic Resection in Patients with Recurrent Hepatocellular Carcinoma and Analysis of Recurrent Types and Their Prognosis: A Single-Center Experience in China

Zhiyong Huang, Bin-yong Liang, Min Xiong, +5

Annals of Surgical Oncology

Recurrent TypesSurgical OncologyHepatologyRepeat Hepatic ResectionCancer Recurrence +10

Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma

Runze Shang, Xinhua Song, Pan Wang, +12

Gut

Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation

Xinhua Song, Hongwei Xu, Pan Wang, +15

Journal of Hepatology

Cancer ResearchFocal Adhesion KinaseSignaling PathwayCholangiocarcinoma DevelopmentMedicine +8

TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis

Bin-yong Liang, Yi Zhou, Manning Qian, +12

Journal of Hepatology

Axis inhibition protein 1 (Axin1) Deletion–Induced Hepatocarcinogenesis Requires Intact β‐Catenin but Not Notch Cascade in Mice

Yu Qiao, Jingxiao Wang, Eylul Karagoz, +12

Hepatology

Notch CascadeCancer BiologyHcc DevelopmentTumor BiologyTranscriptional Regulation +16

β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma

Yi Zhang, Hongwei Xu, Guofei Cui, +1

Gastroenterology

Oncologyβ-Catenin SustainsOncogenic AgentMedicineBiliary Cancer +8

Ku80 functions as a tumor suppressor in hepatocellular carcinoma by inducing S-phase arrest through a p53-dependent pathway

Shuang Wei, Min Xiong, Daqian Zhan, +5

Carcinogenesis

Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice

Yi Zhang, Bin-yong Liang, Xinhua Song, +6

American Journal Of Pathology

Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans

Haichuan Wang, Xinhua Song, Haotian Liao, +17

Hepatology