Erythroferrone inhibits the induction of hepcidin by BMP6

João Arezes, Niall Foy, Kirsty McHugh, +14

Blood

Hepcidin-Induced Hypoferremia Is a Critical Host Defense Mechanism against the Siderophilic Bacterium Vibrio vulnificus

João Arezes, Grace Jung, Victoria Gabayan, +6

Cell Host & Microbe

Virulence FactorHepcidinPathogenesisImmunologyBacteriology +8

Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non–transferrin-bound iron

D Stefanova, Antoan Raychev, João Arezes, +8

Blood

Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin

Pei Jin Lim, Tiago L. Duarte, João Arezes, +21

Nature Metabolism

Iron DeficiencyIron HomoeostasisBiochemistryHeme HomeostasisNatural Sciences +10

Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia

João Arezes, Niall Foy, Kirsty McHugh, +16

Blood

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

Sarah Gooding, Sam W.Z. Olechnowicz, Emma V. Morris, +16

Nature Communications

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

Sant‐Rayn Pasricha, Pei Jin Lim, Tiago L. Duarte, +25

Nature Communications

Physiological implications of NTBI uptake by T lymphocytes

Jorge P. Pinto, João Arezes, Vera Dias, +8

Frontiers in Pharmacology

Non-Transferrin-Bound Iron (NTBI) Uptake by T Lymphocytes: Evidence for the Selective Acquisition of Oligomeric Ferric Citrate Species

João Arezes, Mónica Costa, Inês Vieira, +10

PLoS ONE

Iron MetabolismImmunologyBlood CellIron DeficiencyRedox Biology +16

Antiviral activity of bone morphogenetic proteins and activins

Lucy A. Eddowes, Kinda Al-Hourani, Narayan Ramamurthy, +27

Nature Microbiology

SclerostinBone Morphogenic ProteinAntiviral ActivityOsteoarthritisMedicine +3