Co-ordinated ocular development from human iPS cells and recovery of corneal function

Ryuhei Hayashi, Yuki Ishikawa, Yuzuru Sasamoto, +10

Nature

Human Ips CellsDevelopmental BiologyOphthalmologyCo-ordinated Ocular DevelopmentOcular Tissue +8

Generation of Corneal Epithelial Cells from Induced Pluripotent Stem Cells Derived from Human Dermal Fibroblast and Corneal Limbal Epithelium

Ryuhei Hayashi, Yuki Ishikawa, Miyuki Ito, +8

PLoS ONE

Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells

Ryuhei Hayashi, Yuki Ishikawa, Ryousuke Katori, +7

Nature Protocols

Tissue EngineeringHuman Ips CellsDevelopmental BiologyOphthalmologyMedicine +7

A Novel Gelatin Hydrogel Carrier Sheet for Corneal Endothelial Transplantation

Ryou Watanabe, Ryuhei Hayashi, Yu Kimura, +5

Tissue Engineering Part A

Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors

Kazushige Murayama, Tohru Kimura, Masayoshi Tarutani, +7

Oncogene

Lineage PlasticityCutaneous BiologyEpidermal ProgenitorsDermatologyMedicine +2

Generation of 3D lacrimal gland organoids from human pluripotent stem cells

Ryuhei Hayashi, Toru Okubo, Yuji Kudo, +9

Nature

Tissue EngineeringRegenerative MedicineInduced Pluripotent Stem CellLacrimal Gland OrganoidsEngineering +12

Maintenance and Distribution of Epithelial Stem/Progenitor Cells after Corneal Reconstruction Using Oral Mucosal Epithelial Cell Sheets

Takeshi Soma, Ryuhei Hayashi, Hiroaki Sugiyama, +4

PLoS ONE

Regenerative MedicineDevelopmental BiologyOphthalmologyCorneal DystrophyMedicine +13

Identification and Potential Application of Human Corneal Endothelial Progenitor Cells

Susumu Hara, Ryuhei Hayashi, Takeshi Soma, +4

Stem Cells and Development

Regenerative MedicineOcular DiseaseDevelopmental BiologyOphthalmologyExperimental Ophthalmology +13

Enrichment of corneal epithelial stem/progenitor cells using cell surface markers, integrin α6 and CD71

Ryuhei Hayashi, Masayuki Yamato, Teiko Saito, +4

Biochemical and Biophysical Research Communications

OphthalmologyMedicineOcular TissueStem Cell ResearchIntegrin α6 +5

Induced pluripotent stem-cell-derived corneal epithelium for transplant surgery: a single-arm, open-label, first-in-human interventional study in Japan

Takeshi Soma, Yoshinori Oie, Hiroshi Takayanagi, +10

The Lancet