Large-scale pancreatic cancer detection via non-contrast CT and deep learning

Kai Cao, Yingda Xia, Jiawen Yao, +33

Nature Medicine

Artificial IntelligenceEngineeringMachine LearningDigital PathologyDiagnosis +17

Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation

Yimeng Zhang, Youwei Xu, Yan Qi, +9

Toxicology

InflammationAnti-inflammatoryMedicineLipid PeroxidationImmunology +8

Dioscin, a natural steroid saponin, induces apoptosis and DNA damage through reactive oxygen species: A potential new drug for treatment of glioblastoma multiforme

Linlin Lv, Lingli Zheng, Deshi Dong, +6

Food and Chemical Toxicology

Neuro-oncologyNatural Steroid SaponinOncologyReactive Oxygen SpeciesMedicine +10

CXCR2 promotes breast cancer metastasis and chemoresistance via suppression of AKT1 and activation of COX2

Xu Han, Fengjuan Lin, Ziliang Wang, +6

Cancer Letters

Breast Cancer MetastasisTumor BiologyBreast OncologyMedicineCancer Cell Biology +7

Triglyceride-glucose index associated with the risk of cardiovascular disease: the Kailuan study

Qian Liu, Haozhe Cui, Yihan Ma, +3

Endocrine

ObesityMetabolic SyndromeHypertensionCardiovascular DiseaseHealth Policy +11

IP3R-Grp75-VDAC1-MCU calcium regulation axis antagonists protect podocytes from apoptosis and decrease proteinuria in an Adriamycin nephropathy rat model

Xu Han, Na Guan, Ya-Li Ren, +7

BMC Nephrology

Protective effects of dioscin against cisplatin‐induced nephrotoxicity via the microRNA‐34a/sirtuin 1 signalling pathway

Yimeng Zhang, Xufeng Tao, Lianhong Yin, +9

British Journal of Pharmacology

A prospective controlled study: minimally invasive stereotactic puncture therapy versus conventional craniotomy in the treatment of acute intracerebral hemorrhage

Houguang Zhou, Yu Zhang, Ling Liu, +6

BMC Neurology

Dioscin alleviates non-alcoholic fatty liver disease through adjusting lipid metabolism via SIRT1/AMPK signaling pathway

Hong Yao, Xufeng Tao, Lina Xu, +6

Pharmacological Research

Metabolic SyndromeHepatologyBiochemistryLipid MetabolismMedicine +9

Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats

Shuai Zhang, Lingli Zheng, Deshi Dong, +7

Food Chemistry

Metabolic SyndromeNutritionFood Bioactive CompoundMedicineLiver Physiology +6