Cynthia Cho

Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity

Paul R. Leger, Dennis X. Hu, Bérenger Biannic et al. · Journal of Medicinal Chemistry · 2020 · 74 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity <i>In Vitro</i> and <i>In Vivo</i>

Yamini M. Ohol, Michael Sun, Gene Cutler et al. · Molecular Cancer Therapeutics · 2020 · 38 citations

Medicine, Oncology, Pharmacology +13

Bronchus-associated macrophages efficiently capture and present soluble inhaled antigens and are capable of local Th2 cell activation

Xin-Zi Tang, Lieselotte S.M. Kreuk, Cynthia Cho et al. · eLife · 2022 · 33 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy

Jeffrey J. Jackson, Grant M. Shibuya, Buvana Ravishankar et al. · Journal of Medicinal Chemistry · 2022 · 12 citations · Full text

Medicine, Oncology, Pharmacology +16