Jayshree L. Hirpara

Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

Chew Hooi Wong, Kartini Iskandar, Sanjiv K. Yadav et al. · PLoS ONE · 2010 · 259 citations · Full text

Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies

Andrea L.A. Wong, Ross A. Soo, Daniel S.W. Tan et al. · Annals of Oncology · 2015 · 166 citations

Refractory Solid Malignancies, Medicine, Cancer Biology +8

Hydrogen Peroxide-Mediated Cytosolic Acidification Is a Signal for Mitochondrial Translocation of Bax during Drug-Induced Apoptosis of Tumor Cells

Kashif Ahmad, Kartini Iskandar, Jayshree L. Hirpara et al. · Cancer Research · 2004 · 129 citations · Full text

Cancer Research, Oncology, Mitochondrial Function +15

Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance

Jayshree L. Hirpara, Jie Qing Eu, Joanna Kia Min Tan et al. · Redox Biology · 2018 · 125 citations · Full text

Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondria

M-V Clément, Jayshree L. Hirpara, Shazib Pervaiz · Cell Death and Differentiation · 2003 · 108 citations · Full text

Tumor Biology, Mitochondrial Function, Intracellular Superoxide +12