Maria A. VanVolkenburg

Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate

Samit K. Bhattacharya, Kim Andrews, Ramsay E. Beveridge et al. · ACS Medicinal Chemistry Letters · 2014 · 67 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +10

Cyclic AMP Phosphodiesterases of Human and Rat Islets of Langerhans: Contributions of Types III and IV to the Modulation of Insulin Secretion

Jeremy C. Parker, Maria A. VanVolkenburg, Robert J. Ketchum et al. · Biochemical and Biophysical Research Communications · 1995 · 59 citations · Full text

Pde Inhibitors, Insulin Signaling, Metabolic Syndrome +17

Plasma glucose levels are reduced in rats and mice treated with an inhibitor of glucose-6-phosphate translocase.

Jeremy C. Parker, Maria A. VanVolkenburg, Carolyn B. Levy et al. · Diabetes · 1998 · 57 citations

Glucose-6-phosphate Translocase, Experimental Pharmacology, Insulin Signaling +19

(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: A potent, selective, orally active dipeptidyl peptidase IV inhibitor

Mark Ammirati, Kim Andrews, David Boyer et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 43 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +9

<i>cis</i>-2,5-Dicyanopyrrolidine Inhibitors of Dipeptidyl Peptidase IV:  Synthesis and in Vitro, in Vivo, and X-ray Crystallographic Characterization

Stephen W. Wright, Mark Ammirati, Kim Andrews et al. · Journal of Medicinal Chemistry · 2006 · 34 citations · Full text

Glycobiology, Chemical Biology, Pharmaceutical Chemistry +16