Repeated low-dose treatment of rats with pilocarpine: low mortality but high proportion of rats developing epilepsy

Maike Glien, Claudia Brandt, Heidrun Potschka, +3

Epilepsy Research

High ProportionPsychoactive DrugMedicineLow MortalityPsychopharmacology +8

Effects of the Novel Antiepileptic Drug Levetiracetam on Spontaneous Recurrent Seizures in the Rat Pilocarpine Model of Temporal Lobe Epilepsy

Maike Glien, Claudia Brandt, Heidrun Potschka, +1

Epilepsia

Epileptogenesis and neuropathology after different types of status epilepticus induced by prolonged electrical stimulation of the basolateral amygdala in rats

Claudia Brandt, Maike Glien, Heidrun Potschka, +2

Epilepsy Research

Different TypesNeuromodulationNeurophysiologyNeuroanatomyMedicine +11

Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists

Andreas Evers, Torsten Haack, M. Lorenz, +10

Journal of Medicinal Chemistry

BiochemistryFunctional SelectivityMedicineDrug DiscoveryPeptide Library +12

Prophylactic treatment with levetiracetam after status epilepticus: Lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats

Claudia Brandt, Maike Glien, Alexandra M. Gastens, +5

Neuropharmacology

Behavioral AlterationsBehavioral NeuroscienceNeuroanatomyNeurophysiologyBehavioral Pharmacology +12

AVE8134, a novel potent PPARα agonist, improves lipid profile and glucose metabolism in dyslipidemic mice and type 2 diabetic rats

Hans Ludwig Schäfer, Wolfgang Linz, Eugen Falk, +6

Acta Pharmacologica Sinica

Identification and Synthesis of Novel Inhibitors of Acetyl-CoA Carboxylase with in Vitro and in Vivo Efficacy on Fat Oxidation

Stefanie Keil, Marco Müller, G. Zöller, +7

Journal of Medicinal Chemistry

Metabolic SyndromeMedicinal ChemistryFat OxidationHuman IsoformsPharmacological Study +13

Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator‐Activated Receptor (PPAR) γ/δ Agonists with High Potency and in vivo Efficacy

Stefanie Keil, Hans Matter, Karl Schönafinger, +7

ChemMedChem

Pau d’arco activates Nrf2-dependent gene expression via the MEK/ERK-pathway

Michelle F. Richter, Angelika F. Winkel, Dietmar Schummer, +5

The Journal of Toxicological Sciences

Reductive StressPau D'arcoTranscriptional RegulationSignal TransductionVivo Pau D'arco +12

Stimulation of Fat Oxidation, but no Sustained Reduction of Hepatic Lipids by Prolonged Pharmacological Inhibition of Acetyl CoA Carboxylase

Maike Glien, Guido Haschke, Katrin Schroeter, +6

Hormone and Metabolic Research

Sustained ReductionFatty Liver DiseaseOxidative StressObesityMetabolic Syndrome +14