Irène Pachón-Angona

Leveraging molecular structure and bioactivity with chemical language models for de novo drug design

Michaël Moret, Irène Pachón-Angona, Leandro Cotos et al. · Nature Communications · 2023 · 145 citations · Full text

Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy

Irène Pachón-Angona, Bernard Refouvelet, Rudolf Andrýs et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2019 · 56 citations · Full text

Synthesis, antioxidant and Aβ anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction

Mohamed Benchekroun, Irène Pachón-Angona, Vincent Luzet et al. · Bioorganic Chemistry · 2018 · 23 citations

Biochemistry, Phytochemical, Lipoic Acid Derivatives +5

Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels

Irène Pachón-Angona, Solene Daniel, Hélène Martin et al. · Molecules · 2020 · 19 citations · Full text

Synthesis of New Ferulic/Lipoic/Comenic Acid-Melatonin Hybrids as Antioxidants and Nrf2 Activators via Ugi Reaction

Irène Pachón-Angona, Hélène Martin, Stecy Chhor et al. · Future Medicinal Chemistry · 2019 · 18 citations