Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities

Risini D. Weeratna, Paul Payette, Marion Jurk, +7

European Journal of Immunology

Cpg OdnImmunologyMolecular BiologyImmunologic MechanismImmunotherapy +20

Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8

Sibylle Tluk, Claudia Schmitz, Svetlana Hamm, +7

The Journal of Experimental Medicine

ImmunologyInnate ImmunitySmall Nuclear RnasImmunotherapyImmune Dysregulation +18

Identification of RNA Sequence Motifs Stimulating Sequence-Specific TLR8-Dependent Immune Responses

Alexandra Forsbach, Jean-Guy Némorin, Carmen Montino, +7

The Journal of Immunology

Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll‐like receptor 9 dependent T helper type 2 biased immune stimulation

Risini D. Weeratna, Marion Jurk, Ulrike Samulowitz, +5

Immunology

Adaptive Immune SystemInnate Immune SystemImmunologyCd4 T Cell ResponsesToll‐like Receptor 9 +20

Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T‐rich phosphorothiate oligodeoxynucleotides

Marion Jurk, Andrea Kritzler, Bettina Schulte, +3

European Journal of Immunology

Innate Immune SystemImmunologyMolecular BiologyHuman Tlr7Innate Immunity +20

Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense

Sterghios Moschos, Manfred Frick, B Keith Taylor, +25

Molecular Therapy

C-Class CpG ODN: sequence requirements and characterization of immunostimulatory activities on mRNA level

Marion Jurk, Bettina Schulte, Andrea Kritzler, +5

Immunobiology

Mrna LevelSignal TransductionProtein ExpressionImmunologyC-class Cpg Odn +5

Modulation of CpG Oligodeoxynucleotide-Mediated Immune Stimulation by Locked Nucleic Acid (LNA)

Jan Stenvang, Eugen Uhlmann, Christian Schetter, +4

Oligonucleotides

Lna OdnsAllergyLocked Nucleic AcidInnate Immune SystemImmunology +12

CpG oligodeoxynucleotides stimulate IFN-γ-inducible protein-10 production in human B cells

Marion Jurk, Ulrike Samulowitz, Grayson B. Lipford, +8

Journal of Endotoxin Research

ImmunologyImmune RegulationMolecular BiologyImmunologic MechanismImmunotherapy +18

The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation

Holger Hackstein, Angela Knoche, Angelika Nockher, +4

Cellular Immunology

InflammationImmunologyAutoimmunityT Cell ImmunityDendritic Cell Biology +5