Akulapalli Sudhakar

Optimized Hydrophobic Interactions and Hydrogen Bonding at the Target-Ligand Interface Leads the Pathways of Drug-Designing

Rohan Patil, Suranjana Das, Ashley Stanley et al. · PLoS ONE · 2010 · 745 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Physiological levels of tumstatin, a fragment of collagen IV α3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via αVβ3 integrin

Yuki Hamano, Michael Zeisberg, Hikaru Sugimoto et al. · Cancer Cell · 2003 · 552 citations · Full text

Medicine, Molecular Medicine, Signal Transduction +10

Neutralization of Circulating Vascular Endothelial Growth Factor (VEGF) by Anti-VEGF Antibodies and Soluble VEGF Receptor 1 (sFlt-1) Induces Proteinuria

Hikaru Sugimoto, Yuki Hamano, David M. Charytan et al. · Journal of Biological Chemistry · 2003 · 532 citations · Full text

Medicine, Nephrology, Pathobiology +17

History of Cancer, Ancient and Modern Treatment Methods

Akulapalli Sudhakar · Journal of Cancer Science & Therapy · 2009 · 500 citations · Full text

Medicine, Oncology, Surgery +16

Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by αvβ3 and α5β1 integrins

Akulapalli Sudhakar, Hikaru Sugimoto, Changqing Yang et al. · Proceedings of the National Academy of Sciences · 2003 · 480 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15