Blimp-1 Orchestrates Plasma Cell Differentiation by Extinguishing the Mature B Cell Gene Expression Program

Arthur L. Shaffer, Kuo‐I Lin, Tracy C. Kuo, +8

Immunity

Protein ExpressionCell RegulationCell SignalingImmunologyCell Fate Determination +5

Blimp-1-Dependent Repression of <i>Pax-5</i> Is Required for Differentiation of B Cells to Immunoglobulin M-Secreting Plasma Cells

Kuo‐I Lin, Cristina Angelin‐Duclos, Tracy C. Kuo, +1

Molecular and Cellular Biology

Lymphocyte DevelopmentPax-5 GeneImmunologyImmune RegulationHumoral Response +19

Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR

Stella Maris Ranuncolo, José M. Polo, Jamil Dierov, +6

Nature Immunology

Dna-damage Sensor AtrLymphoid NeoplasiaLymphocyte DevelopmentImmunologyAdult T-cell Leukemia-lymphoma +5

Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication

Johanna Theruvath, Marie Ménard, Benjamin Smith, +39

Nature Medicine

Tumor EradicationImmunologyImmune Checkpoint InhibitorTumor TargetingImmunotherapy +1

B cell exchange across the blood-brain barrier in multiple sclerosis

H.‐Christian von Büdingen, Tracy C. Kuo, Marina Sirota, +12

Journal of Clinical Investigation

Adaptive Immune SystemNeurological DisorderImmunologyPathologyImmunotherapy +19

Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis

Arumugam Palanichamy, Leonard Apeltsin, Tracy C. Kuo, +10

Science Translational Medicine

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation

Jacob Glanville, Tracy C. Kuo, H.‐Christian von Büdingen, +10

Proceedings of the National Academy of Sciences

ALX148 blocks CD47 and enhances innate and adaptive antitumor immunity with a favorable safety profile

Steven E. Kauder, Tracy C. Kuo, Ons Harrabi, +9

PLoS ONE

Adaptive Immune SystemImmunologyImmunotherapeuticsInnate ImmunityImmunotherapy +16

Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma

Cesar Sommer, Bijan Boldajipour, Tracy C. Kuo, +21

Molecular Therapy

B Lymphocyte-Induced Maturation Protein (Blimp)-1, IFN Regulatory Factor (IRF)-1, and IRF-2 Can Bind to the Same Regulatory Sites

Tracy C. Kuo, Kathryn Calame

The Journal of Immunology