Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1

Abraham Pinter, William Honnen, S A Tilley, +4

Journal of Virology

Virus StructureMonomeric Gp41BiochemistryNatural SciencesHuman Retrovirus +12

Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein

Markus Thali, Craig Furman, David D. Ho, +4

Journal of Virology

Amino AcidsImmunologyPathologyHiv-1 IsolatesViral Structural Protein +19

Inhibition of Virus Attachment to CD4+ Target Cells Is a Major Mechanism of T Cell Line–adapted HIV-1 Neutralization

Sophie Ugolini, Isabelle Mondor, Paul W.H.I. Parren, +4

The Journal of Experimental Medicine

A human monoclonal antibody against the CD4-binding site of HIV1 gp120 exhibits potent, broadly neutralizing activity

S A Tilley, William Honnen, MARY E. RACHO, +2

Research in Virology

Cd4-binding SiteHuman Monoclonal AntibodyHuman RetrovirusImmunologyAntiviral Response +6

Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region

Richard T. Wyatt, Markus Thali, S A Tilley, +5

Journal of Virology

ImmunologyMolecular BiologyAntigen ProcessingViral Structural ProteinImmunotherapy +15

Synergistic Neutralization of HIV-1 by Human Monoclonal Antibodies Against the V3 Loop and the CD4-Binding Site of gp120

S A Tilley, WILLIAM J. HONNEN, MARY E. RACHO, +2

AIDS Research and Human Retroviruses

Cd4-binding SiteImmunologyMolecular BiologySynergistic NeutralizationViral Structural Protein +15

Characterization of neutralization epitopes in the V2 region of human immunodeficiency virus type 1 gp120: role of glycosylation in the correct folding of the V1/V2 domain

Zhiwei Wu, Samuel C. Kayman, William Honnen, +7

Journal of Virology

GlycobiologyImmunologyMolecular BiologyPathologyAntigen Processing +19

A novel, glycan-dependent epitope in the V2 domain of human immunodeficiency virus type 1 gp120 is recognized by a highly potent, neutralizing chimpanzee monoclonal antibody

Shweta Warrier, Abraham Pinter, William Honnen, +3

Journal of Virology

ImmunologyGlycobiologyAntiviral DrugViral Structural ProteinImmunotherapy +15

Synergistic neutralization of human immunodeficiency virus type 1 by a chimpanzee monoclonal antibody against the V2 domain of gp120 in combination with monoclonal antibodies against the V3 loop and the CD4-binding site

S Vijh-Warrier, Abraham Pinter, William Honnen, +1

Journal of Virology

Significant SynergyHiv-1 StrainAllergyNeurovirologyHuman Retrovirus +12

Conformational changes affecting the V3 and CD4-binding domains of human immunodeficiency virus type 1 gp120 associated with env processing and with binding of ligands to these sites

Abraham Pinter, William Honnen, S A Tilley

Journal of Virology

Viral ReplicationCd4-binding SiteImmunologyMolecular BiologyConformational Changes +15