Human platelet lysate biotherapy for traumatic brain injury: preclinical assessment

Ouada Nebie, Kévin Carvalho, Lassina Barro, +13

Brain

Extensive characterization of the composition and functional activities of five preparations of human platelet lysates for dedicated clinical uses

Liling Delila, Yu‐Wen Wu, Ouada Nebie, +4

Platelets

ImmunologyPlatelet PathobiologyHpl PreparationsThrombosisTranslational Medicine +18

Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription

Isabel Paiva, Lucrezia Cellai, Céline Mériaux, +31

Journal of Clinical Investigation

The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates

Ouada Nebie, David Devos, Valérie Vingtdeux, +9

Journal of Biomedical Science

Characterization and Chromatographic Isolation of Platelet Extracellular Vesicles from Human Platelet Lysates for Applications in Neuroregenerative Medicine

Ariunjargal Nyam‐Erdene, Ouada Nebie, Liling Delila, +5

ACS Biomaterials Science & Engineering

Heat-treated human platelet pellet lysate modulates microglia activation, favors wound healing and promotes neuronal differentiation<i>in vitro</i>

Ouada Nebie, Lassina Barro, Yu‐Wen Wu, +6

Platelets

ImmunologyPeripheral NervesNeuroinflammationInflammationRegenerative Medicine +21

A purified human platelet pellet lysate rich in neurotrophic factors and antioxidants repairs and protects corneal endothelial cells from oxidative stress

Rifa Widyaningrum, Thierry Burnouf, Ouada Nebie, +2

Biomedicine & Pharmacotherapy

Platelet extracellular vesicles are efficient delivery vehicles of doxorubicin, an anti-cancer drug: preparation and in vitro characterization

Yu‐Wen Wu, Deng-Yao Lee, Yeh‐Lin Lu, +7

Platelets

Neuroprotective activity of a virus‐safe nanofiltered human platelet lysate depleted of extracellular vesicles in Parkinson's disease and traumatic brain injury models

Liling Delila, Ouada Nebie, Nhi Thao Ngoc Le, +9

Bioengineering & Translational Medicine

NanoparticlesNanotherapeuticsEngineeringBrain AdministrationBio-based Nanomaterials +18

Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson’s disease models

Liling Delila, Ouada Nebie, Nhi Thao Ngoc Le, +9

Journal of Biomedical Science