Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

Frances Connor, David Bertwistle, P. Joseph Mee, +5

Nature Genetics

Knockout MouseChromatinGenome InstabilityDna DamageSomatic Variant +7

Physical and Functional Interactions of the Arf Tumor Suppressor Protein with Nucleophosmin/B23

David Bertwistle, Masataka Sugimoto, Charles J. Sherr

Molecular and Cellular Biology

Protein FunctionCell RegulationFunctional InteractionsMedicineMolecular Biology +11

Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification

Andrew Tutt, Anastasia Gabriel, David Bertwistle, +5

Current Biology

ChromatinGenome InstabilityCytogeneticsGeneticsChromosome Biology +6

N-terminal polyubiquitination and degradation of the Arf tumor suppressor

Mei-Ling Kuo, Willem den Besten, David Bertwistle, +2

Genes & Development

Transcriptional RegulationUbiquitin-proteasome PathwayMolecular RegulationArf UbiquitinationMedicine +11

Interaction between the Product of the Breast Cancer Susceptibility Gene <i>BRCA2</i> and DSS1, a Protein Functionally Conserved from Yeast to Mammals

Nicola J. Marston, William J. Richards, David A. Hughes, +3

Molecular and Cellular Biology

Breast OncologyGeneticsHuman Brca2Molecular BiologyCancer Biology +14

Nuclear location and cell cycle regulation of the BRCA2 protein.

David Bertwistle, S Swift, NJ Marston, +5

PubMed

GeneticsMolecular BiologyCell CycleNuclear LocationCancer Biology +17

Negative control of <i>Xenopus</i> GATA-2 by activin and noggin with eventual expression in precursors of the ventral blood islands

Maggie Walmsley, Matthew Guille, David Bertwistle, +3

Development

Arf‐dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye

Ricardo L.A. Silva, J. Derek Thornton, Amy C. Martin, +4

The EMBO Journal

GATA factors and the origins of adult and embryonic blood in Xenopus: responses to retinoic acid

David Bertwistle, Maggie Walmsley, E.Mary Read, +2

Mechanisms of Development

BiologyAnimal PhysiologyGata FactorsEmbryonic BloodDevelopmental Biology +8

Cell cycle and genetic background dependence of the effect of loss of BRCA2 on ionizing radiation sensitivity

Andrew Tutt, Frances Connor, David Bertwistle, +4

Oncogene

Radiation OncologyRadiation MedicineGeneticsGenetic Background DependenceRadiation Exposure +6