Tetsuya Kouno

Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway

Tetsuya Kouno, Xiao Liu, Huayi Zhao et al. · Journal of Biological Chemistry · 2022 · 52 citations · Full text

Cholangiopathies, Oxidative Stress, Molecular Pharmacology +22

Engineered bacteria producing aryl‐hydrocarbon receptor agonists protect against ethanol‐induced liver disease in mice

Tetsuya Kouno, Su-Ling Zeng, Yanhan Wang et al. · Alcohol Clinical and Experimental Research · 2023 · 30 citations · Full text

Specific Enzyme Complex of β-1,4-Galactosyltransferase-II and Glucuronyltransferase-P Facilitates Biosynthesis of N-linked Human Natural Killer-1 (HNK-1) Carbohydrate

Tetsuya Kouno, Yasuhiko Kizuka, Naoki Nakagawa et al. · Journal of Biological Chemistry · 2011 · 26 citations · Full text

Glycobiology, Molecular Biology, Specific Enzyme Complex +25

Ghrelin O-acyltransferase knockout mice show resistance to obesity when fed high-sucrose diet

Tetsuya Kouno, Nobuteru Akiyama, Takahito Ito et al. · Journal of Endocrinology · 2015 · 25 citations · Full text

Nutrition, Metabolic Disorder, Food Intake +22

Reduced intake of carbohydrate prevents the development of obesity and impaired glucose metabolism in ghrelin O-acyltransferase knockout mice

Tetsuya Kouno, Nobuteru Akiyama, Kumiko Fujieda et al. · Peptides · 2016 · 19 citations

Obesity, Nutrition, Metabolic Syndrome +14