Alice Legru

4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors

Laurent Gavara, Laurent Sevaille, Filomena De Luca et al. · European Journal of Medicinal Chemistry · 2020 · 42 citations · Full text

4-Amino-1,2,4-triazole-3-thione-derived Schiff Bases, Medicinal Chemistry, Biochemistry +6

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

Alice Legru, Federica Verdirosa, Jean‐François Hernandez et al. · European Journal of Medicinal Chemistry · 2021 · 26 citations · Full text

Medicinal Chemistry, Antimicrobial Drug Discovery, Re-sensitization Activity +13

Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates

Alice Legru, Federica Verdirosa, Yen Vo‐Hoang et al. · Journal of Medicinal Chemistry · 2022 · 23 citations · Full text

4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition

Laurent Gavara, Federica Verdirosa, Alice Legru et al. · Biomolecules · 2020 · 19 citations · Full text

4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors

Laurent Gavara, Alice Legru, Federica Verdirosa et al. · Bioorganic Chemistry · 2021 · 18 citations · Full text

4-Alkyl-1,2,4-triazole-3-thione Analogues, Medicinal Chemistry, Antimicrobial Drug Discovery +7