LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia

Yusuke Tarumoto, Bin Lu, Tim D.D. Somerville, +7

Molecular Cell

Hematological MalignancyMixed-phenotype Acute LeukemiaAcute Myeloid LeukemiaSalt-inducible KinasesSystems Biology +5

Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo

Yusuke Tarumoto, Shan Lin, Jinhua Wang, +10

Blood

A TFIID-SAGA Perturbation that Targets MYB and Suppresses Acute Myeloid Leukemia

Yali Xu, Joseph P. Milazzo, Tim D.D. Somerville, +6

Cancer Cell

Hematological MalignancyMixed-phenotype Acute LeukemiaImmunologyHematologyAutoimmunity +6

A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence

Bin Lü, Olaf Klingbeil, Yusuke Tarumoto, +15

Cancer Cell

Hematological MalignancyChromatinTranscriptional RegulationTranscription Factor AddictionMll Promoter Sequence +8

Tel1^ATM and Rad3^ATR phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast

Harutake Yamazaki, Yusuke Tarumoto, Fuyuki Ishikawa

Genes & Development

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

Sumiko Takao, Lauren Forbes, Masahiro Uni, +11

eLife

GeneticsMolecular BiologyTranscription Factor ComplexesAberrant Myb ComplexTumor Biology +14

KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements

Yan Zi Au, Muxin Gu, Étienne De Braekeleer, +11

Leukemia

Fission yeast Stn1 is crucial for semi-conservative replication at telomeres and subtelomeres

Masahiro Takikawa, Yusuke Tarumoto, Fuyuki Ishikawa

Nucleic Acids Research

GeneticsMolecular BiologyMolecular GeneticsSemi-conservative Dna ReplicationRestrictive Temperature +14

Receptor for Activated C-Kinase (RACK1) Homolog Cpc2 Facilitates the General Amino Acid Control Response through Gcn2 Kinase in Fission Yeast

Yusuke Tarumoto, Junko Kanoh, Fuyuki Ishikawa

Journal of Biological Chemistry

HIRA, a Conserved Histone Chaperone, Plays an Essential Role in Low-dose Stress Response via Transcriptional Stimulation in Fission Yeast

Moeko Chujo, Yusuke Tarumoto, Koichi Miyatake, +2

Journal of Biological Chemistry

Conserved Histone ChaperoneChromatinFission YeastChromatin RemodelingGenetics +8