6-(3,4-Dichlorophenyl)-1-[(Methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: A New Potent and Selective Triple Reuptake Inhibitor

Fabrizio Micheli, Paolo Cavanni, Daniele Andreotti, +28

Journal of Medicinal Chemistry

PharmacotherapyNew SeriesHeterocycle ChemistryExperimental PharmacologyPharmaceutical Chemistry +14

1-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes: A New Series of Potent and Selective Triple Reuptake Inhibitors

Fabrizio Micheli, Paolo Cavanni, Roberto Arban, +23

Journal of Medicinal Chemistry

Medicinal ChemistryHeterocyclicPharmacological StudyMedicineSelective Triple +13

Synthesis and SAR of substituted tetrahydrocarbazole derivatives as new NPY-1 antagonists

Romano Di Fabio, Riccardo Giovannini, Barbara Bertani, +9

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistrySubstituted Tetrahydrocarbazole DerivativesDerivative (Chemistry)New Npy-1 AntagonistsNatural Sciences +7

Novel Stereocontrolled Addition of Allylmetal Reagents to α-Imino Esters:  Efficient Synthesis of Chiral Tetrahydroquinoline Derivatives

Romano Di Fabio, Giuseppe Alvaro, Barbara Bertani, +5

The Journal of Organic Chemistry

Combinatorial ChemistryBioorganic ChemistryOrganic ChemistryChemistryMedicinal Chemistry +17

Phenylethynyl-pyrrolo[1,2-a]pyrazine: A new potent and selective tool in the mGluR5 antagonists arena

Fabrizio Micheli, Barbara Bertani, Andrea Bozzoli, +9

Bioorganic & Medicinal Chemistry Letters

BiochemistryMedicineSelective ToolRational Drug DesignMechanism Of Action +6

Design and Synthesis of Novel Tricyclic Benzoxazines as Potent 5-HT_1A/B/D Receptor Antagonists Leading to the Discovery of 6-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-4<i>H</i>-imidazo[5,1-<i>c</i>][1,4]benzoxazine-3-carboxamide (GSK588045)

Steven M. Bromidge, Roberto Arban, Barbara Bertani, +19

Journal of Medicinal Chemistry

Stable expression and functional characterization of a human nicotinic acetylcholine receptor with α6β2 properties: discovery of selective antagonists

Anna Maria Capelli, Laura Castelletti, Yu Hua Chen, +8

British Journal of Pharmacology

6-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: Dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors

Steven M. Bromidge, Barbara Bertani, Manuela Borriello, +11

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistrySerotonin Reuptake InhibitorsBiochemistryMedicineNatural Sciences +5

Exploration of the Amine Terminus in a Novel Series of 1,2,4-Triazolo-3-yl-azabicyclo[3.1.0]hexanes as Selective Dopamine D₃Receptor Antagonists

Fabrizio Micheli, Luca Arista, Barbara Bertani, +14

Journal of Medicinal Chemistry

Enantiomerically pure tetrahydroquinoline derivatives as in vivo potent antagonists of the glycine binding site associated to the NMDA receptor

Romano Di Fabio, Elvira Tranquillini, Barbara Bertani, +13

Bioorganic & Medicinal Chemistry Letters

BiochemistryFunctional SelectivityMedicinePure Tetrahydroquinoline DerivativesMechanism Of Action +8