Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis.

Kiyohiro Ando, Takashi Moriyama, Luca G. Guidotti, +5

The Journal of Experimental Medicine

ImmunologyPathologyCell DeathImmunologic MechanismTransgenic Mouse Model +17

Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice.

Luca G. Guidotti, Kiyohiro Ando, M V Hobbs, +4

Proceedings of the National Academy of Sciences

Viral ImmunityImmunologyHepatitis BPathologyTransgenic Mice +15

Activation of AMP-activated Protein Kinase Induces p53-dependent Apoptotic Cell Death in Response to Energetic Stress

Rintaro Okoshi, Toshinori Ozaki, Hideki Yamamoto, +7

Journal of Biological Chemistry

Polo-like Kinase 1 (Plk1) Inhibits p53 Function by Physical Interaction and Phosphorylation

Kiyohiro Ando, Toshinori Ozaki, Hideki Yamamoto, +5

Journal of Biological Chemistry

Cell DeathPhysical InteractionCell CycleCancer BiologyTumor Biology +14

Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL

Kiyohiro Ando, Kazumasa Hiroishi, Takehisa Kaneko, +6

The Journal of Immunology

Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice

Reinhold Schirmbeck, W Böhm, Kiyohiro Ando, +2

Journal of Virology

VaccinationVaccine DevelopmentNative Hbsag ParticlesViral HepatitisVaccine Target +11

Class I-restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo.

Kiyohiro Ando, Luca G. Guidotti, S Wirth, +7

The Journal of Immunology

SQSTM1 Is a Pathogenic Target of 5q Copy Number Gains in Kidney Cancer

Lianjie Li, Chuan Shen, Eijiro Nakamura, +18

Cancer Cell

UrologyGenitourinary CancerMedicinePathologyCancer Genomics +8

CTL access to tissue antigen is restricted in vivo.

Kiyohiro Ando, Luca G. Guidotti, Anna Cerny, +2

The Journal of Immunology

ImmunologyPathologyAntigen ProcessingImmune SystemImmunotherapy +18

Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas

Shinichi Yamada, Miki Ohira, Hiroshi Horie, +16

Oncogene

HepatologyMedicineLiver PhysiologyHistopathologyHigh Expression +10