A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

Matthias Heinig, Enrico Petretto, Chris Wallace, +40

Nature

Type 1Systems BiologySignal TransductionAutoimmune DiseaseDisease Mechanism +11

High salt reduces the activation of IL-4– and IL-13–stimulated macrophages

Katrina J. Binger, Matthias Gebhardt, Matthias Heinig, +18

Journal of Clinical Investigation

ImmunologyRenal InflammationImmune SystemHigh IntakeImmunotherapy +14

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing

Henrike Maatz, Marvin Jens, Martin Liss, +14

Journal of Clinical Investigation

Heart FailureEngineeringGeneticsRna SplicingMolecular Biology +20

Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy

Matthias Heinig, Michiel Adriaens, Sebastian Schäfer, +28

Genome biology

Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis

Franziska Lange, Estelle Bajtner, Carola Rintisch, +3

Annals of the Rheumatic Diseases

Natural variation of histone modification and its impact on gene expression in the rat genome

Carola Rintisch, Matthias Heinig, Anja Bauerfeind, +15

Genome Research

Genomes and phenomes of a population of outbred rats and its progenitors

Amelie Baud, Victor Guryev, Oliver Hummel, +72

Scientific Data

histoneHMM: Differential analysis of histone modifications with broad genomic footprints

Matthias Heinig, Maria Colomé‐Tatché, Aaron Taudt, +6

BMC Bioinformatics

Positional cloning of the <i>Igl</i> genes controlling rheumatoid factor production and allergic bronchitis in rats

Carola Rintisch, Jacqueline Ameri, Peter Olofsson, +2

Proceedings of the National Academy of Sciences

AsthmaInflammatory Lung DiseaseLung InflammationImmunologyImmune Regulation +21

Finemapping of the arthritis QTL Pia7 reveals co-localization with Oia2 and the APLEC locus

Carola Rintisch, Tiina Kelkka, Ulrika Norin, +3

Genes and Immunity

RheumatologyArthritis Qtl Pia7GeneticsOsteoarthritisAplec Locus +4