Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

Pierre De Rossi, Virginie Buggia-Prévot, Benjamin L.L. Clayton, +15

Molecular Neurodegeneration

Rescue of impaired sociability and anxiety-like behavior in adult cacna1c-deficient mice by pharmacologically targeting eIF2α

Zeeba D. Kabir, Alicia Che, Delaney K. Fischer, +6

Molecular Psychiatry

Adult Cacna1c-deficient MiceBehavioral NeuroscienceMedicineBehavioural PharmacologyBehavioral Pharmacology +7

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration

Dolores Del Prete, Richard C. Rice, Anjali M. Rajadhyaksha, +1

Journal of Biological Chemistry

Neurodegenerative DiseasesProtein FunctionAlzheimer's DiseaseMolecular BiologyDegenerative Pathology +9

Cacna1c in the Prefrontal Cortex Regulates Depression-Related Behaviors via REDD1

Zeeba D. Kabir, Anni S. Lee, Caitlin E. Burgdorf, +12

Neuropsychopharmacology

Synaptic PlasticityNeurobiological MechanismPsychiatryBehavioral NeurosciencePrefrontal Cortex +9

Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease

Robert J. Andrew, Celia Fernández-Sanz, Molly Stanley, +15

Proceedings of the National Academy of Sciences

Transgenic Mouse ModelsSynaptic TransmissionBace1 ExpressionAmyloid Precursor ProteinSynaptic Signaling +18

Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine

Jin Xu, Zhigang Lu, Ankita Narayan, +13

Journal of Clinical Investigation

Morphine TolerancePain MedicinePharmacotherapySocial SciencesMolecular Pharmacology +14

Reduction of the expression of the late-onset Alzheimer’s disease (AD) risk-factor BIN1 does not affect amyloid pathology in an AD mouse model

Robert J. Andrew, Pierre De Rossi, Phuong Nguyen, +8

Journal of Biological Chemistry

Enhancing VTA Cav1.3 L-type Ca2+ channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens

Arlene Martínez-Rivera, Thomas F. Tropea, Thomas P. Giordano, +8

Molecular Psychiatry

Behavioral NeuroscienceAddictionAmpa Receptor MechanismsPhysiologyNeurotransmitter +8

Arthroscopically Repaired Bucket-Handle Meniscus Tears: Patient Demographics, Postoperative Outcomes, and a Comparison of Success and Failure Cases

Bryan M. Saltzman, Eric J. Cotter, Kevin C. Wang, +6

Cartilage

Rescue of Learning and Memory Deficits in the Human Nonsyndromic Intellectual Disability Cereblon Knock-Out Mouse Model by Targeting the AMP-Activated Protein Kinase–mTORC1 Translational Pathway

Charlotte C. Bavley, Richard C. Rice, Delaney K. Fischer, +10

Journal of Neuroscience