Tsung-Hsien Chang

Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-κB activation

Tsung-Hsien Chang, Ching‐Len Liao, Yi‐Ling Lin · Microbes and Infection · 2005 · 231 citations

Transcriptional Regulation, Systems Biology, Molecular Virology +14

Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

Tsung-Hsien Chang, Toru Kubota, Mayumi Matsuoka et al. · PLoS Pathogens · 2009 · 212 citations · Full text

Tripartite Motif-Containing Protein 28 Is a Small Ubiquitin-Related Modifier E3 Ligase and Negative Regulator of IFN Regulatory Factor 7

Qiming Liang, Hongying Deng, Xiaojuan Li et al. · The Journal of Immunology · 2011 · 180 citations · Full text

Negative Regulator, Molecular Regulation, Immunology +16

Virus Infection Triggers SUMOylation of IRF3 and IRF7, Leading to the Negative Regulation of Type I Interferon Gene Expression

Toru Kubota, Mayumi Matsuoka, Tsung-Hsien Chang et al. · Journal of Biological Chemistry · 2008 · 161 citations · Full text

Sumo Modification, Genetics, Innate Immune System +20

Hydroxychloroquine-Inhibited Dengue Virus Is Associated with Host Defense Machinery

Li-Fong Wang, You-Sheng Lin, Nan-Chieh Huang et al. · Journal of Interferon & Cytokine Research · 2014 · 123 citations · Full text