Concepedia

Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-κB activation

Tsung-Hsien Chang, Ching‐Len Liao, Yi‐Ling Lin

Microbes and Infection · 2005 · 236 citations · 57 references

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References

57

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov et al. · Nature · 2001 · 6.1K citations

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa et al. · Nature Immunology · 2004 · 3.9K citations

, , +16

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.3K citations · Full text

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IKKε and TBK1 are essential components of the IRF3 signaling pathway

Katherine A. Fitzgerald, Sarah M. McWhirter, Daniel C. Rowe et al. · Nature Immunology · 2003 · 2.7K citations

, , +6

Triggering the Interferon Antiviral Response Through an IKK-Related Pathway

Sonia Sharma, Benjamin R. tenOever, Nathalie Grandvaux et al. · Science · 2003 · 1.7K citations

, , +17