Lochana M. Seenappa

Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial

Shubham Pant, Zev A. Wainberg, Colin D. Weekes et al. · Nature Medicine · 2024 · 235 citations · Full text

Medicine, Immunology, Oncology +17

Lymph node targeted multi-epitope subunit vaccine promotes effective immunity to EBV in HLA-expressing mice

Vijayendra Dasari, Lisa K. McNeil, Kirrilee Beckett et al. · Nature Communications · 2023 · 59 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

A lymph node–targeted Amphiphile vaccine induces potent cellular and humoral immunity to SARS-CoV-2

Martin P. Steinbuck, Lochana M. Seenappa, Aniela Jakubowski et al. · Science Advances · 2021 · 54 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates

Lochana M. Seenappa, Aniela Jakubowski, Martin P. Steinbuck et al. · npj Vaccines · 2022 · 17 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

AMPLIFY-201, a first-in-human safety and efficacy trial of adjuvant ELI-002 2P immunotherapy for patients with high-relapse risk with KRAS G12D- or G12R-mutated pancreatic and colorectal cancer.

Eileen M. O’Reilly, Zev A. Wainberg, Colin D. Weekes et al. · Journal of Clinical Oncology · 2023 · 17 citations

Life Sciences, Immunology, Oncology +17