ADMETlab 3.0: an updated comprehensive online ADMET prediction platform enhanced with broader coverage, improved performance, API functionality and decision support

Li Fu, Shaohua Shi, Jiacai Yi, +11

Nucleic Acids Research

Multipotent AChE and BACE-1 inhibitors for the treatment of Alzheimer's disease: Design, synthesis and bio-analysis of 7-amino-1,4-dihydro-2 H -isoquilin-3-one derivates

Xiongjie Zhao, Da-min Gong, Yuren Jiang, +3

European Journal of Medicinal Chemistry

Medicinal ChemistryAlzheimer's DiseaseMultipotent AcheBiochemistryMedicine +10

Biosynthesis of thiocarboxylic acid-containing natural products

Liao‐Bin Dong, Jeffrey D. Rudolf, Dingding Kang, +7

Nature Communications

Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferase 4/5

Ayad A. Al-Hamashi, Dongxing Chen, Youchao Deng, +2

Acta Pharmaceutica Sinica B

Late-Stage Functionalization of Platensimycin Leading to Multiple Analogues with Improved Antibacterial Activity in Vitro and in Vivo

Youchao Deng, Xiang Weng, Yuling Li, +7

Journal of Medicinal Chemistry

Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant <i>Staphylococcus aureus</i> in Topical and Systemic Infection Mouse Models

Meng Su, Lin Qiu, Youchao Deng, +8

Molecular Pharmaceutics

Staphylococcus AureusAntimicrobial ChemotherapyBacterial PathogensDrug ResistanceWound Care +18

Semisynthesis of Platensimycin Derivatives with Antibiotic Activities in Mice via Suzuki–Miyaura Cross-Coupling Reactions

Youchao Deng, Meng Su, Dingding Kang, +7

Journal of Medicinal Chemistry

Biomimetic Stereoselective Sulfa-Michael Addition Leads to Platensimycin and Platencin Sulfur Analogues against Methicillin-Resistant <i>Staphylococcus aureus</i>

Lin Qiu, Kai Tian, Zhongqing Wen, +7

Journal of Natural Products

A new flavonol from <i>Sophora tonkinensis</i>

Youchao Deng, Kang Xu, Yuanliang Zhou, +3

Journal of Asian Natural Products Research

PhytoalexinBiosynthesisBiochemistrySophora TonkinensisPhytopharmacology +6

The semi-synthesis, biological evaluation and docking analysis of the oxime, hydrazine and hydrazide derivatives of platensimycin

Youchao Deng, Dingding Kang, Jie Shi, +7

MedChemComm

Combinatorial ChemistryBioorganic ChemistryOrganic ChemistryPharmaceutical ChemistryChemical Derivative +18