R. M. Thomas

Discovery of 3-[2-(Imidazo[1,2-<i>b</i>]pyridazin-3-yl)ethynyl]-4-methyl-<i>N</i>-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a Potent, Orally Active Pan-Inhibitor of Breakpoint Cluster Region-Abelson (BCR-ABL) Kinase Including the T315I Gatekeeper Mutant

Wei‐Sheng Huang, Chester A. Metcalf, Raji Sundaramoorthi et al. · Journal of Medicinal Chemistry · 2010 · 357 citations · Full text

Drug Target, Immunology, Molecular Biology +25

A novel, mild and facile reductive cleavage of allyl ethers by system

R. M. Thomas, G. Hari Mohan, D. S. Iyengar · Tetrahedron Letters · 1997 · 53 citations

Cross-coupling Reaction, Engineering, Alkene Metathesis +7

9-(Arenethenyl)purines as Dual Src/Abl Kinase Inhibitors Targeting the Inactive Conformation: Design, Synthesis, and Biological Evaluation

Wei‐Sheng Huang, Xiaotian Zhu, Yihan Wang et al. · Journal of Medicinal Chemistry · 2009 · 46 citations · Full text

Immunology, Pharmacotherapy, Active Enzyme Conformation +19

The high pressure mediated intramolecular diels-alder reaction of furans: Factors controlling cycloaddition with monoactivated dienophiles.

Laurence M. Harwood, S. A. LEEMING, Neil S. Isaacs et al. · Tetrahedron Letters · 1988 · 29 citations

Intramolecular Diels-alder Reaction, Engineering, Biochemistry +4

An efficient and selective deprotection of allyl ethers by a CeCl3.7H2O NaI system

R. M. Thomas, G. Sudhakar Reddy, D. S. Iyengar · Tetrahedron Letters · 1999 · 28 citations