Reza Ebrahimighaei

Antiproliferative and Antimigratory Effects of a Novel YAP–TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking

Sarah A. Smith, Richard B. Sessions, Deborah K. Shoemark et al. · Journal of Medicinal Chemistry · 2019 · 80 citations · Full text

Pharmacotherapy, Pharmaceutical Chemistry, Tumor Biology +23

Combined role for YAP-TEAD and YAP-RUNX2 signalling in substrate-stiffness regulation of cardiac fibroblast proliferation

Reza Ebrahimighaei, Graciela B. Sala‐Newby, Claire Hudson et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2022 · 32 citations · Full text

Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD

Madeleine C. McNeill, Jason Wray, Graciela B. Sala‐Newby et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2020 · 29 citations · Full text

Elevated cyclic-AMP represses expression of exchange protein activated by cAMP (EPAC1) by inhibiting YAP-TEAD activity and HDAC-mediated histone deacetylation

Reza Ebrahimighaei, Madeleine C. McNeill, Sarah A. Smith et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2019 · 17 citations · Full text

Chromatin, Hdac-mediated Histone Deacetylation, Signal Transduction +11

Extracellular matrix stiffness controls cardiac fibroblast proliferation via the nuclear factor-Y (NF-Y) transcription factor

Reza Ebrahimighaei, Nathalie Tarassova, Samuel Charles Bond et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2023 · 14 citations · Full text