Lorenzo Tortolina

A novel Bim-BH3-derived Bcl-XL inhibitor: Biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity

Raffaella Ponassi, Barbara Biasotti, Valeria Tomati et al. · Cell Cycle · 2008 · 31 citations · Full text

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies

Lorenzo Tortolina, David J. Duffy, Massimo Maffei et al. · Oncotarget · 2014 · 29 citations · Full text

Engineering, Biomedical Research, Cancer Biology +25

Inhibition of a protein‐protein interaction between INI1 and c‐Myc by small peptidomimetic molecules inspired by Helix‐1 of c‐Myc: identification of a new target of potential antineoplastic interest

Luca Bagnasco, Lorenzo Tortolina, Barbara Biasotti et al. · The FASEB Journal · 2007 · 28 citations

Drug Target, Molecular Biology, A Myc Binding +23

Sequence specific peptidomimetic molecules inhibitors of a protein–protein interaction at the helix 1 level of c‐Myc

Erika Nieddu, A Melchiori, Maria Pia Pescarolo et al. · The FASEB Journal · 2005 · 27 citations

Myc Motif, Molecular Biology, Peptide Science +19

Computational quantification of global effects induced by mutations and drugs in signaling networks of colorectal cancer cells

Sara Sommariva, Giacomo Caviglia, Silvia Ravera et al. · Scientific Reports · 2021 · 11 citations · Full text