David J. Duffy

Problems, challenges and promises: perspectives on precision medicine

David J. Duffy · Briefings in Bioinformatics · 2015 · 135 citations · Full text

Translational Medicine, Biomedical Data Integration, Data Science +11

Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas

Kai-Oliver Henrich, Sebastian Bender, Maral Saadati et al. · Cancer Research · 2016 · 123 citations · Full text

Histone Modifications, Epigenetic Change, Dna Methylation +25

Wnt signaling promotes oral but suppresses aboral structures in <i>Hydractinia</i> metamorphosis and regeneration

David J. Duffy, Günter Plickert, Timo Kuenzel et al. · Development · 2010 · 103 citations · Full text

Biology, Developmental Biology, Signal Transduction +15

Induced stem cell neoplasia in a cnidarian by ectopic expression of a POU domain transcription factor

R. Cathriona Millane, Justyna Kanska, David J. Duffy et al. · Development · 2011 · 84 citations

Biology, Cell Lineage, Lineage Plasticity +15

GSK3 Inhibitors Regulate <i>MYCN</i> mRNA Levels and Reduce Neuroblastoma Cell Viability through Multiple Mechanisms, Including p53 and Wnt Signaling

David J. Duffy, Aleksandar Krstić, Thomas Schwarzl et al. · Molecular Cancer Therapeutics · 2013 · 82 citations · Full text

Multiple Mechanisms, Neuroblastoma Cell Viability, Pathology +17