Robyn M. Barfield

Aldehyde Tag Coupled with HIPS Chemistry Enables the Production of ADCs Conjugated Site-Specifically to Different Antibody Regions with Distinct in Vivo Efficacy and PK Outcomes

Penelope M. Drake, Aaron E. Albers, Jeanne Baker et al. · Bioconjugate Chemistry · 2014 · 210 citations · Full text

Immunology, Adcs Conjugated Site-specifically, Conjugation Site +22

Hydrazino-Pictet-Spengler Ligation as a Biocompatible Method for the Generation of Stable Protein Conjugates

Paresh Agarwal, Romas Kudirka, Aaron E. Albers et al. · Bioconjugate Chemistry · 2013 · 157 citations

Bioorganic Chemistry, Engineering, Protein Assembly +22

Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag

Jason E. Hudak, Robyn M. Barfield, Gregory W. de Hart et al. · Angewandte Chemie International Edition · 2012 · 150 citations · Full text

Bioorganic Chemistry, Protein Assembly, Molecular Biology +16

CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity

C. Kimberly Tsui, Robyn M. Barfield, Curt R. Fischer et al. · Nature Chemical Biology · 2019 · 80 citations

Antibody–drug Conjugate Toxicity, Medicine, Immunology +6

Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion

Patrick G. Holder, Lesley Jones, Penelope M. Drake et al. · Journal of Biological Chemistry · 2015 · 65 citations · Full text

Engineering, Aldehyde Dehydrogenase, Biochemistry +7