Xiulong Shen

Generation of DNA-Damaging Reactive Oxygen Species via the Autoxidation of Hydrogen Sulfide under Physiologically Relevant Conditions: Chemistry Relevant to Both the Genotoxic and Cell Signaling Properties of H₂S

Marjorie A. Hoffman, Anuruddha Rajapakse, Xiulong Shen et al. · Chemical Research in Toxicology · 2012 · 48 citations · Full text

Dna Damage, Lipid Peroxidation, Molecular Biology +17

Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat

Liande Li, Xiulong Shen, Zhongtian Liu et al. · Nucleic Acid Therapeutics · 2018 · 44 citations · Full text

Diverse Chemical Modifications, Frataxin Protein Expression, Molecular Biology +19

Computer-aided de novo ligand design and docking/molecular dynamics study of Vitamin D receptor agonists

Xiulong Shen, Midori Takimoto‐Kamimura, Jing Wei et al. · Journal of Molecular Modeling · 2011 · 27 citations

Medicinal Chemistry, Biochemistry, Functional Selectivity +9

Targeting 3′ and 5′ untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression

Yanjie Li, Jixue Li, Jun Wang et al. · Nucleic Acids Research · 2021 · 25 citations · Full text

Molecular Biology, Analytical Ultracentrifugation, Protein Synthesis +20

Duplex RNAs and ss-siRNAs Block RNA Foci Associated with Fuchs' Endothelial Corneal Dystrophy

Jiaxin Hu, Xiulong Shen, Frank Rigo et al. · Nucleic Acid Therapeutics · 2019 · 24 citations · Full text

Ocular Disease, Ophthalmology, Corneal Dystrophy +14