Anastazia M. Older Aguilar

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C

Thorsten Graef, Achim K. Moesta, Paul J. Norman et al. · The Journal of Experimental Medicine · 2009 · 235 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Evolution of Killer Cell Ig-Like Receptor (<i>KIR</i>) Genes: Definition of an Orangutan <i>KIR</i> Haplotype Reveals Expansion of Lineage III KIR Associated with the Emergence of MHC-C

Lisbeth A. Guethlein, Anastazia M. Older Aguilar, Laurent Abi-Rached et al. · The Journal of Immunology · 2007 · 86 citations · Full text

Life Sciences, Evolutionary Biology, Genetics +17

Mutation at Positively Selected Positions in the Binding Site for HLA-C Shows That KIR2DL1 Is a More Refined but Less Adaptable NK Cell Receptor Than KIR2DL3

Hugo G. Hilton, Luca Vago, Anastazia M. Older Aguilar et al. · The Journal of Immunology · 2012 · 84 citations · Full text

Life Sciences, Genetics, Immunology +17

Humans Differ from Other Hominids in Lacking an Activating NK Cell Receptor That Recognizes the C1 Epitope of MHC Class I

Achim K. Moesta, Thorsten Graef, Laurent Abi-Rached et al. · The Journal of Immunology · 2010 · 80 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Coevolution of Killer Cell Ig-Like Receptors with HLA-C To Become the Major Variable Regulators of Human NK Cells

Anastazia M. Older Aguilar, Lisbeth A. Guethlein, Erin J. Adams et al. · The Journal of Immunology · 2010 · 78 citations · Full text

Life Sciences, Cell Biology, Immunology +17