Esther A. Zaal

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat

Isabelle Becher, Thilo Werner, Carola Doce et al. · Nature Chemical Biology · 2016 · 250 citations

Biosynthesis, Engineering, Biochemistry +9

Bortezomib resistance in multiple myeloma is associated with increased serine synthesis

Esther A. Zaal, Wei Wu, Gerrit Jansen et al. · Cancer & Metabolism · 2017 · 184 citations · Full text

A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer

Haojie Jin, Siying Wang, Esther A. Zaal et al. · eLife · 2020 · 171 citations · Full text

Pharmacotherapy, Tumor Biology, Medicinal Chemistry +18

Proteasome Activation by Small Molecules

Yves Leestemaker, Annemieke de Jong, Katharina F. Witting et al. · Cell chemical biology · 2017 · 143 citations · Full text

Protein Function, Biochemistry, Protein Folding +8

Anti-tumour immunity induces aberrant peptide presentation in melanoma

Osnat Bartok, Abhijeet Pataskar, Remco Nagel et al. · Nature · 2020 · 142 citations · Full text

Immune Evasion, Tumor Immunology, Cancer Immunosurveillance +7