Kevin J. Metcalf

Design of a mucin-selective protease for targeted degradation of cancer-associated mucins

Kayvon Pedram, D. Judy Shon, Gabrielle S. Tender et al. · Nature Biotechnology · 2023 · 81 citations · Full text

Type III secretion as a generalizable strategy for the production of full‐length biopolymer‐forming proteins

Anum Azam, Cheng Li, Kevin J. Metcalf et al. · Biotechnology and Bioengineering · 2015 · 42 citations

Protein Secretion, Engineering, Protein Assembly +19

A machine learning strategy for the identification of key <i>in silico</i> descriptors and prediction models for IgG monoclonal antibody developability properties

Andrew B. Waight, David Příhoda, Rojan Shrestha et al. · mAbs · 2023 · 36 citations · Full text

Directed Evolution of Brain-Derived Neurotrophic Factor for Improved Folding and Expression in Saccharomyces cerevisiae

Michael Burns, Thomas M. Malott, Kevin J. Metcalf et al. · Applied and Environmental Microbiology · 2014 · 30 citations · Full text

Protein Secretion, Bdnf Mutants, Engineering +20

Using Transcriptional Control To Increase Titers of Secreted Heterologous Proteins by the Type III Secretion System

Kevin J. Metcalf, Casey Finnerty, Anum Azam et al. · Applied and Environmental Microbiology · 2014 · 25 citations · Full text

Environmental Signaling, Protein Secretion, Microbial Pathogens +24