Saskia Eckert

Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetylcholinesterase by highly toxic organophosphorus compounds

Saskia Eckert, Peter Eyer, Harald Mückter et al. · Biochemical Pharmacology · 2006 · 49 citations

Toxic Organophosphorus Compounds, Biochemistry, Medicine +6

Reversible inhibition of acetylcholinesterase by carbamates or huperzine A increases residual activity of the enzyme upon soman challenge

Saskia Eckert, Peter Eyer, Franz Worek · Toxicology · 2006 · 34 citations

Soman Challenge, Reversible Inhibition, Biochemistry +8

Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity

Saskia Eckert, Peter Eyer, Nadja M. Herkert et al. · Biochemical Pharmacology · 2007 · 30 citations

Biochemistry, Medicine, Physiology +9

Development of a dynamic model for real-time determination of membrane-bound acetylcholinesterase activity upon perfusion with inhibitors and reactivators

Saskia Eckert, Peter Eyer, Harald Mückter et al. · Biochemical Pharmacology · 2006 · 27 citations

Inhibitory Activity, Proteinlipid Interaction, Biochemistry +11

Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors

Nadja M. Herkert, Saskia Eckert, Peter Eyer et al. · Toxicology · 2008 · 23 citations

Residual Activity, Soman Challenge, Biochemistry +8