Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

Hiroyuki Mori, Reiko Hanada, Toshikatsu Hanada, +7

Nature Medicine

ObesityMetabolic SyndromeEnergy HomeostasisLeptin SensitivityGastrointestinal Peptide Hormone +11

Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

Takehiro Torisu, Kumiko Torisu, In Hye Lee, +12

Nature Medicine

InflammationEndothelial Cell PathobiologyCell AutophagyDevelopmental BiologyVon Willebrand Factor +10

Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN-γ on STAT3 and Smads

Kentaro Tanaka, Kenji Ichiyama, Masayuki Hashimoto, +11

The Journal of Immunology

T-regulatory CellDefective Th17 DifferentiationImmunologyImmune RegulationImmunologic Mechanism +24

Comparison of the microbial community structure between inflamed and non‐inflamed sites in patients with ulcerative colitis

Atsushi Hirano, Junji Umeno, Yasuharu Okamoto, +10

Journal of Gastroenterology and Hepatology

Intact endothelial autophagy is required to maintain vascular lipid homeostasis

Kumiko Torisu, Krishna K. Singh, Takehiro Torisu, +10

Aging Cell

MitophagyAutophagic FluxLipid PeroxidationOxidative StressInflammation +14

The dual function of hepatic SOCS3 in insulin resistance <i>in vivo</i>

Takehiro Torisu, Naoichi Sato, Daigo Yoshiga, +5

Genes to Cells

Quality of life and physical fitness in an 85-year-old population

Yutaka Takata, Toshihiro Ansai, Inho Soh, +11

Archives of Gerontology and Geriatrics

Quality Of LifePhysical ActivityKinesiologyHealthy AgingPhysical Fitness +8

Leucine-rich alpha-2 glycoprotein is a potential biomarker to monitor disease activity in inflammatory bowel disease receiving adalimumab: PLANET study

Shinichiro Shinzaki, Katsuyoshi Matsuoka, Hiroki Tanaka, +20

Journal of Gastroenterology

Relationship between tooth loss and mortality in 80-year-old Japanese community-dwelling subjects

Toshihiro Ansai, Yutaka Takata, Inho Soh, +8

BMC Public Health

Suppressor of cytokine signaling 1 protects mice against concanavalin A–induced hepatitis by inhibiting apoptosis

Takehiro Torisu, Mako Nakaya, Satoko Watanabe, +11

Hepatology